Infertility is a deeply emotional journey that affects millions of couples worldwide. For many, the root cause lies in poor egg quality, often influenced by age, lifestyle, or cellular dysfunction. Traditional IVF and ICSI procedures help many couples conceive, but for some, repeated failures indicate that the issue may be more deeply rooted — at the cellular level.
This is where cytoplasmic transfer, an advanced fertility innovation, brings new hope. At Prashanth IVF, one of India’s leading fertility centers, this breakthrough technique has been successfully used to rejuvenate eggs and enhance embryo development — improving the chances of pregnancy for women who had previously lost hope.
What Is Cytoplasmic Transfer?
Cytoplasmic transfer is a microscopic procedure used in assisted reproduction to enhance the quality of a woman’s eggs. It involves transferring a small amount of healthy cytoplasm — the inner fluid of a donor’s egg — into the recipient’s egg.
The cytoplasm contains mitochondria, enzymes, and growth factors that are essential for cell energy, stability, and proper embryo development. In women with weakened or aged eggs, these mitochondrial deficiencies can lead to failed fertilization or poor embryo growth. By introducing healthy cytoplasmic material, the egg’s vitality is restored, resulting in higher success rates in IVF.
Essentially, cytoplasmic transfer gives the egg a “cellular energy boost”, allowing it to behave like a younger, healthier egg.
Who Can Benefit from Cytoplasmic Transfer?
Cytoplasmic transfer is recommended for women who face the following fertility challenges:
- Repeated IVF or ICSI failures
- Poor egg quality or low mitochondrial function
- Women above 35 years of age
- History of embryonic arrest or slow embryo growth
- Genetic or chromosomal abnormalities in previous embryos
- Unexplained infertility after multiple ART cycles
How Does Cytoplasmic Transfer Work?
The procedure is performed under advanced embryology lab conditions with precise micromanipulation tools. Below is a step-by-step overview of how cytoplasmic transfer is carried out:
Egg Retrieval:
Mature eggs are collected from both the donor and the patient after ovarian stimulation.
Cytoplasm Extraction:
Using microscopic tools, embryologists extract a tiny amount of cytoplasm from the healthy donor egg.
Transfer into Recipient Egg:
The extracted cytoplasm is then carefully injected into the patient’s egg, ensuring that the egg’s nucleus (which contains the genetic material) remains intact.
Fertilization:
The rejuvenated egg is fertilized with the partner’s sperm through IVF or ICSI methods.
Embryo Culturing:
The resulting embryos are observed for quality and development. Healthy embryos are selected for transfer to the uterus.
Embryo Transfer and Pregnancy:
After monitoring, the best embryo(s) are transferred into the uterus, and the patient is followed up for implantation and pregnancy success.
This delicate process requires advanced lab infrastructure and a team of highly skilled embryologists — both of which are hallmarks of Prashanth IVF.
How Cytoplasmic Transfer Helps Improve Fertility
Cytoplasmic transfer directly addresses mitochondrial dysfunction, which is often linked to failed IVF outcomes. By introducing fresh, healthy cytoplasm, this technique:
Restores Cellular Energy: Healthy mitochondria power the egg’s cellular functions, improving fertilization potential.
Improves Egg Quality: Revitalized eggs produce better-quality embryos with stronger development potential.
Enhances Embryo Viability: Promotes balanced cellular division, reducing chromosomal errors.
Boosts IVF Success Rates: Patients who’ve faced multiple IVF failures often see improved results.
Delays Age-Related Decline: Helps older women achieve pregnancy without needing donor eggs.
In simple terms, cytoplasmic transfer helps an older or weaker egg behave like a young, energetic one — giving couples renewed hope for conception.
Why Choose Prashanth IVF for Cytoplasmic Transfer?
Prashanth IVF is one of India’s most trusted names in fertility care — combining advanced reproductive technology with compassionate patient support. The hospital is now offering this state of the art procedure overseen by their Australian collaboration. Couples suffering from unexplained infertility, recurrent implantation failure, highly fragmented embryos, advance aged patients and those with mitochondrial disorders are the best candidates for this new treatment method. Cytoplasmic transfer is a fresh new hope for infertile couples in India.Here’s why it stands out for cytoplasmic transfer treatments:
Expertise and Experience
Led by experienced fertility specialists and embryologists, Prashanth IVF has 43 years of expertise in handling complex reproductive cases, cytoplasmic transfer, mitochondrial therapy, and advanced IVF cycles.
Cutting-Edge Laboratory
The embryology lab is equipped with next-generation tools for micromanipulation and embryo monitoring, ensuring precision and high success rates.
Personalized Care
Every couple’s fertility journey is unique. Prashanth IVF designs customized treatment plans based on individual health, age, and fertility history to maximize outcomes.
Global Standards of Success
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